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Merck

HBA2

hemoglobin, alpha 2

Synonyms:
HBH
Species:
Human HBA2 (3040), Rat Hba2 (360504), Horse HBA2 (100036558)
UniProtKB ID:
Gene ID:
  • Human(3040) Summary: The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. [provided by RefSeq, Jul 2008]
  • Rat(360504) hemoglobin, alpha 2
  • Horse(100036558) hemoglobin, alpha 2

Custom & Knockdown Gene Products

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Small Molecule - Allosteric Modulator

Product Number
Description
Species
B7273
Bezafibrate, ≥98%, solid,
Species
mouse, human

Small Molecule - Antagonist

Product Number
Description
Species
560510
3-(Diethylamino)propyl isothiocyanate, 97%,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
SAB1303638
ANTI-HBA2 (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
flow cytometry
immunohistochemistry
western blot
SAB5500116
Anti-Haemoglobin Alpha Chain antibody, Rabbit monoclonal, clone SP212, recombinant, expressed in proprietary host, affinity isolated antibody,
Species Reactivity
human
Application
flow cytometry
immunohistochemistry
western blot

Kits

Product Number
Description
Species
MAK115
Hemoglobin Assay Kit, sufficient for 250 colorimetric tests,
Species
mouse, rat, human

Proteins

Product Number
Description
Species
H0266
Hemoglobin A2, Ferrous Stabilized human, lyophilized powder,
Species
human
H7379
Hemoglobin human, lyophilized powder,
Species
human

esiRNA

Product Number
Description
Species
EHU146971
MISSION® esiRNA, targeting human HBA2, HBA1,
Species
human