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Merck

GLDC

glycine dehydrogenase (decarboxylating)

Synonyms:
GCE, GCSP, HYGN1
Species:
UniProtKB ID:
Gene ID:
  • Human(2731) Summary: Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).[provided by RefSeq, Jan 2010]
  • Mouse(104174) glycine decarboxylase
  • Rat(309312) glycine dehydrogenase (decarboxylating)
  • Zebrafish(321621) glycine dehydrogenase (decarboxylating)
  • domestic cat(101100163) glycine dehydrogenase (decarboxylating)
  • cow(507688) glycine dehydrogenase (decarboxylating)
  • Horse(100060355) glycine dehydrogenase (decarboxylating)
  • dog(481534) glycine dehydrogenase (decarboxylating)
  • chicken(374222) glycine dehydrogenase (decarboxylating)
  • sheep(101117476) glycine dehydrogenase (decarboxylating)
  • Domestic Rabbit(100343694) glycine dehydrogenase (decarboxylating)
  • domestic guinea pig(100714862) glycine dehydrogenase (decarboxylating)
  • naked mole-rat(101725465) glycine dehydrogenase (decarboxylating)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-GLDC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
ANTI-GLDC (N-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-GLDC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-GLDC antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot