GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
ECA4, EJM, EJM5
Human GABRA1 (2554), Mouse Gabra1 (14394), Rat Gabra1 (29705), Zebrafish gabra1 (768183), dog GABRA1 (489143), domestic cat GABRA1 (100286792), chicken GABRA1 (374214), cow GABRA1 (780973), sheep GABRA1 (101117759), naked mole-rat Gabra1 (101719179)
- Human(2554) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(14394) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
- Rat(29705) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- Zebrafish(768183) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- dog(489143) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- domestic cat(100286792) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- chicken(374214) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- cow(780973) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- sheep(101117759) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- naked mole-rat(101719179) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- domestic guinea pig(100721626) gamma-aminobutyric acid (GABA) A receptor, alpha 1
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Small Molecule - Agonist
Small Molecule - Allosteric Modulator
Zaleplon solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
human
Small Molecule - Antagonist
Antibodies
Anti-GABA Antibody, from rabbit, purified by affinity chromatography,
all, rat
ELISA
immunohistochemistry
immunohistochemistry
Monoclonal Anti-GABA antibody produced in mouse, clone GB-69, ascites fluid,
wide range
ELISA
dot blot
immunofluorescence
immunohistochemistry
dot blot
immunofluorescence
immunohistochemistry
Anti-GABA Antibody, clone 5A9, clone 5A9, Chemicon®, from mouse,
mammals
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Small Molecule - Ligand
Small Molecule - Mixed Agonist/Antagonist
Phenol solution, Equilibrated with 10 mM Tris HCl, pH 8.0, 1 mM EDTA, BioReagent, for molecular biology,
human
Phenol solution, BioReagent, Saturated with 0.01 M citrate buffer, pH 4.3 ± 0.2, for molecular biology,
human