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Merck

CD68

CD68 molecule

Synonyms:
GP110, LAMP4, SCARD1
Species:
UniProtKB ID:
Gene ID:
  • Human(968) Summary: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(12514) CD68 antigen
  • Rat(287435) Cd68 molecule
  • naked mole-rat(101698291) CD68 molecule
  • domestic guinea pig(100712726) CD68 molecule
  • sheep(101102500) CD68 molecule
  • cow(504960) CD68 molecule
  • Horse(100034045) CD68 molecule
  • domestic cat(101099002) CD68 molecule
  • dog(489476) CD68 molecule

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CD68 antibody produced in mouse, clone Y1/82A,
Species Reactivity
human
Application
flow cytometry
Milli-Mark® Anti-CD68-FITC Antibody, clone KP1, clone KP1, Milli-Mark®, from mouse,
Species Reactivity
human
Application
flow cytometry
Anti-CD68 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-CD68 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL1338, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-CD68 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL1346, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CD68, RP11-186B7.4,
Species
human
MISSION® esiRNA, targeting mouse Cd68,
Species
mouse