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Merck

AKR7A2

aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)

Synonyms:
AFAR, AFAR1, AFB1-AR1, AKR7
Species:
UniProtKB ID:
Gene ID:
  • Human(8574) Summary: The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. [provided by RefSeq, Oct 2011]
  • Rat(171445) aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
  • chicken(419471) aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
  • cow(511996) aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
  • domestic cat(101089785) aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
  • dog(478210) aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
  • naked mole-rat(101705538) aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-AKR7A2 antibody produced in mouse, clone 2A6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-AKR7A2 antibody produced in mouse, clone 2H3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)

western blot
Anti-AKR7A2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-AKR7A2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-AKR7A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human AKR7A2,
Species
human