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Merck

Reproductive toxicity of the glycol ethers.

Toxicology (1983-06-01)
B D Hardin
ZUSAMMENFASSUNG

The glycol ethers are an important and widely used class of solvents. Recent studies have demonstrated that ethylene glycol monomethyl ether (EGME), ethylene glycol dimethyl ether (EGdiME), ethylene glycol monoethyl ether (EGEE), and ethylene glycol monoethyl ether acetate (EGEEA) are teratogenic. Other studies have demonstrated that testicular atrophy or infertility follow treatment of males with EGME, ethylene glycol monomethyl ether acetate (EGMEA), EGEE, EGEEA, diethylene glycol dimethyl ether (diEGdiME), and diethylene glycol monoethyl ether (diEGEE). Experimental data are reviewed and structure-activity relationships are speculated upon.

MATERIALIEN
Produktnummer
Marke
Produktbeschreibung

Sigma-Aldrich
Di(ethylenglycol)ethylether, ≥99%