- A rapid route to aminocyclopropanes via carbamatoorganozinc carbenoids.
A rapid route to aminocyclopropanes via carbamatoorganozinc carbenoids.
Angewandte Chemie (International ed. in English) (2013-08-06)
Shingo Ishikawa, Tom D Sheppard, Jarryl M D'Oyley, Akio Kamimura, William B Motherwell
PMID23913871
ZUSAMMENFASSUNG
Easy as 1,2,3: Reaction of methyl carbamate, triethyl orthoformate, and readily available alkenes provides a highly practical preparation of protected aminocyclopropanes. The reaction proceeds with preferential cis addition to alkenes, and cleavage of the methyl carbamate gives the free aminocyclopropanes as their HI salts.
MATERIALIEN