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  • [The influence of food on the bioavailability of drugs on the example of sulfamethoxydiazine (author's transl)].

[The influence of food on the bioavailability of drugs on the example of sulfamethoxydiazine (author's transl)].

Arzneimittel-Forschung (1980-01-01)
H S Kaumeier
ZUSAMMENFASSUNG

It is demonstrated that the bioavailability of sulfamethoxydiazine (Durenat), taken as an example, is much better when administered simultaneously with a test meal than when given in the fasting state. Also a high-lipid meal in comparison with a high-protein or high-carbohydrate meal considerably improves the bioavailability of sulfamethoxydiazone. Food as well as the composition of food are likely to have short-term and long-term consequences on absorption and biotransformation and therefore influence the bioavailability of drugs.

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Marke
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