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  • Enzymatic peptide synthesis in organic solvent mediated by gels of copolymerized acrylic derivatives of alpha-chymotrypsin and polyoxyethylene.

Enzymatic peptide synthesis in organic solvent mediated by gels of copolymerized acrylic derivatives of alpha-chymotrypsin and polyoxyethylene.

International journal of peptide and protein research (1991-09-01)
V Fulcrand, R Jacquier, R Lazaro, P Viallefont
ZUSAMMENFASSUNG

Copolymers of acrylated derivatives of alpha-chymotrypsin and polyethylene glycol (PEG) have been prepared and used as biocatalysts for the synthesis of model peptides in organic solvent containing a low quantity of water. Other peptide couplings have been tried to point out the chemico- and stereoselectivity and examples of segment couplings are given.

MATERIALIEN
Produktnummer
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Produktbeschreibung

Sigma-Aldrich
Acryloylchlorid, ≥97%, contains ~400 ppm phenothiazine as stabilizer
Sigma-Aldrich
Acryloylchlorid, 97.0%, contains <210 ppm MEHQ as stabilizer