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Prenylflavonoids and phloroglucinol derivatives from hops (Humulus lupulus).

Journal of natural products (2005-02-01)
Feng Zhao, Yuki Watanabe, Hajime Nozawa, Akihiro Daikonnya, Keiji Kondo, Susumu Kitanaka
ZUSAMMENFASSUNG

The ethyl acetate soluble fraction of hops (Humulus lupulus) showed potent inhibitory activity on the production of nitric oxide (NO) induced by a combination of LPS and IFN-gamma. Four known prenylflavonoids (1-4) and a new prenylflavonoid (5), hulupinic acid (6), lupulone (7), and its six new derivatives (8-13) were isolated from the active fraction. The structures were determined on the basis of physiochemical properties and spectroscopic analysis. Their inhibitory activities on the production of NO in macrophage RAW 264.7 cells were examined.

MATERIALIEN
Produktnummer
Marke
Produktbeschreibung

Sigma-Aldrich
Xanthohumol from hop (Humulus lupulus), ≥96% (HPLC)