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USP

Cholinchlorid

United States Pharmacopeia (USP) Reference Standard

Synonym(e):

(2-Hydroxyethyl)trimethylammoniumchlorid

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About This Item

Lineare Formel:
(CH3)3N(Cl)CH2CH2OH
CAS-Nummer:
67-48-1
Molekulargewicht:
139.62
Beilstein:
3563126
MDL-Nummer:
MFCD00011721
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329749389
NACRES:
NA.24

Qualität

pharmaceutical primary standard

Hersteller/Markenname

USP

mp (Schmelzpunkt)

302-305 °C (dec.) (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

SMILES String

[Cl-].C[N+](C)(C)CCO

InChI

1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1

InChIKey

SGMZJAMFUVOLNK-UHFFFAOYSA-M

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung



  • Extraction of Bioactive Compounds: Choline chloride, combined with sucrose in natural deep eutectic solvents, facilitates the formation of aqueous biphasic systems. These systems are applied in drug extraction processes to improve efficiency and selectivity, particularly in pharmaceutical applications (Ghaffari et al., 2024).


  • Extraction of α-Glucosidase Inhibitors: Utilizing choline chloride-based deep eutectic solvents significantly enhances the selective extraction of α-glucosidase inhibitors from waste seeds. This application is particularly valuable in the development of therapeutic agents for diabetes management, showcasing its versatility in pharmaceutical extraction processes (Liu et al., 2024).


Substrate

Cholin-Acetyltransferase-Substrat

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

USP issued SDS can be found here.
Sales restrictions may apply.

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Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Xinyin Jiang et al.
Journal of cellular physiology, 229(8), 1016-1027 (2014-03-22)
Maternal choline intake during gestation may influence placental function and fetal health outcomes. Specifically, we previously showed that supplemental choline reduced placental and maternal circulating concentrations of the anti-angiogenic factor, fms-like tyrosine kinase-1 (sFLT1), in pregnant women as well as
Zhuo Li et al.
Biochimica et biophysica acta, 1840(7), 2112-2122 (2014-03-19)
Choline kinase has three isoforms encoded by the genes Chka and Chkb. Inactivation of Chka in mice results in embryonic lethality, whereas Chkb(-/-) mice display neonatal forelimb bone deformations. To understand the mechanisms underlying the bone deformations, we compared the
O Hemminki et al.
International journal of cancer, 134(12), 2878-2890 (2013-11-20)
At present, it is not possible to reliably identify patients who will benefit from oncolytic virus treatments. Conventional modalities such as computed tomography (CT), which measure tumor size, are unreliable owing to inflammation-induced tumor swelling. We hypothesized that magnetic resonance
Brook T Chernet et al.
Oncotarget, 5(10), 3287-3306 (2014-05-17)
The microenvironment is increasingly recognized as a crucial aspect of cancer. In contrast and complement to the field's focus on biochemical factors and extracellular matrix, we characterize a novel aspect of host:tumor interaction - endogenous bioelectric signals among non-excitable somatic
James L Mills et al.
The American journal of clinical nutrition, 100(4), 1069-1074 (2014-09-23)
Low maternal choline intake and blood concentration may be risk factors for having a child with a neural tube defect (NTD); however, the data are inconsistent. This is an important question to resolve because choline, if taken periconceptionally, might add
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