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Merck

T2027

Sigma-Aldrich

Anti-Transferrin antibody produced in goat

whole antiserum

Synonym(e):

Anti-HEL-S-71p, Anti-PRO1557, Anti-PRO2086, Anti-TFQTL1

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About This Item

MDL-Nummer:
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

goat

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

whole antiserum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Enthält

15 mM sodium azide

Speziesreaktivität

human

Verpackung

antibody small pack of 25 μL

Methode(n)

indirect ELISA: 1:50,000
quantitative precipitin assay: 3.2-4.8 mg/mL

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... TF(7018)

Allgemeine Beschreibung

Transferrin is a bilobed glycoprotein. The polypeptide chain of transferrin is composed of two homologous lobes i.e N- and C- lobes. Each lobe is made of two domains N1, N2 and C1, C2 which are linked by a hinge. It has two specific sites for binding of Fe3+.

Anwendung

Anti-Transferrin antibody has been used:
  • in quantitative precipitin assay
  • in enzyme linked immunosorbent assay (ELISA)
  • in western blotting
  • in immunoblotting

Anti-Transferrin antibody produced in goat was used in western blotting analysis of HEK293 cell extracts.

Biochem./physiol. Wirkung

Transferrin is the major iron transporter protein that binds Fe(+3). The transferring-iron import system consists of a TonB dependent transporter (TbpA), and a lipoprotein co-receptor (TbpB) and both proteins work together in the transport of iron across the membrane.
Transferrin plays a major role in providing iron as a source for haemoglobin synthesis. It binds to the transferrin receptor 1(TfR1).

Angaben zur Herstellung

treated to remove lipoproteins

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Cole P Anderson et al.
Biochimica et biophysica acta, 1823(9), 1468-1483 (2012-05-23)
Cellular iron homeostasis is maintained by iron regulatory proteins 1 and 2 (IRP1 and IRP2). IRPs bind to iron-responsive elements (IREs) located in the untranslated regions of mRNAs encoding protein involved in iron uptake, storage, utilization and export. Over the
New iron acquisition system in Bacteroidetes
Manfredi P, et al.
Infection and Immunity, 83(1), 300-310 (2015)
Nicholas Noinaj et al.
Molecular microbiology, 86(2), 246-257 (2012-09-11)
Two pathogenic species within the genus Neisseria cause the diseases gonorrhoea and meningitis. While vaccines are available to protect against four N. meningitidis serogroups, there is currently no commercial vaccine to protect against serogroup B or against N. gonorrhoeae. Moreover, the available
Hypoglycosylation is a common finding in antithrombin deficiency in the absence of a SERPINC 1 gene defect
de la Morena-Barrio M E, et al.
Journal of Thrombosis and Haemostasis, 14(8), 1549-1560 (2016)
Receptor-mediated activation of a proinsulin-transferrin fusion protein in hepatoma cells.
Wang, Y., et al.
J. Controlled Release, 155, 386-392 (2011)

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