SAB4300149

Anti-phospho-HIST1H3D (pSer¹⁰) antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-H3/b antibody produced in rabbit, Anti-H3FB antibody produced in rabbit, Anti-histone cluster 1, H3d antibody produced in rabbit
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: ~17 kDa
• Speziesreaktivität: rat, human, mouse
• Konzentration: 1 mg/mL
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• Isotyp: IgG
• Immunogene Sequenz: (R-K-SP-T-G)
• NCBI-Hinterlegungsnummer: NP_003521.2
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pSer10)
• Angaben zum Gen: human ... HIST1H3D(8351)

Beschreibung

Immunogen

Peptide sequence around phosphorylation site of serine 10 (R-K-S(p)-T-G), according to the protein HIST1H3D.

Leistungsmerkmale und Vorteile

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Zielbeschreibung

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable