I0879

Inosin-5′-Triphosphat Trinatriumsalz

≥95%

• Synonym(e): ITP
• Empirische Formel (Hill-System): C₁₀H₁₂Na₃N₄O₁₄P₃
• CAS-Nummer: 35908-31-7
• Molekulargewicht: 574.11
• MDL-Nummer: MFCD00084678
• UNSPSC-Code: 41106305
• PubChem Substanz-ID: 24895910
• NACRES: NA.51

Eigenschaften

• Assay: ≥95%
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: [Na].OC1C(O)C(OC1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n2cnc3C(=O)N=CNc23
• InChI: 1S/C10H15N4O14P3.Na.H/c15-6-4(1-25-30(21,22)28-31(23,24)27-29(18,19)20)26-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;/h2-4,6-7,10,15-16H,1H2,(H,21,22)(H,23,24)(H,11,12,17)(H2,18,19,20);;
• InChIKey: RIERCUPIZLBNFQ-UHFFFAOYSA-N
• Angaben zum Gen: human ... HRAS(3265)

Beschreibung

Anwendung

Inosine 5′-triphosphate (ITP) is used in studies on the impact of deamination of ATP and GTP by various enzymes and chemical processes. ITP may be used as a substrate to study the specificity and kinetics of nucleoside-5′-triphosphatase and ATPase. ITP is also used to study activation of various ATPases and GTPases.

Inosine 5′-triphosphate trisodium salt has been used to investigate its influence on the chromosome aberration rate, the mitotic rate, sister-chromatid exchange (SCE) frequency, the proportion of first (X1), second (X2) and third (X3) division metaphases of human peripheral lymphocytes.

Biochem./physiol. Wirkung

Inosine 5′-triphosphate (ITP) has the ability to support the initiation of effector system. It can prevent guanosine 5′-triphosphate (GTP) hydrolysis, that is catalysed by transducin (TD). ITP can proficiently induce secretion in permeabilized cells than GTP. Instead of GTP, ITP can be used for the initiation and the elongation steps of reovirus transcription. ITP can also replace GTP in the activation of G-protein.

Angaben zur Herstellung

Prepared from Bacterial ATP

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable