Alle Fotos(1)

Dokumente

GW21442

Anti-DPP4 antibody produced in chicken

Name: Anti-DPP4 antibody produced in chicken
Brand: SIGMA

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti-CD26, Anti-Dipeptidyl peptidase 4

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise

Alle Fotos(1)

About This Item

MDL-Nummer:

MFCD01094453

UNSPSC-Code:

12352203

NACRES:

NA.41

Biologische Quelle

chicken

Qualitätsniveau

200

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

rat, mouse, human

Hersteller/Markenname

Genway 15-288-21442

Methode(n)

immunocytochemistry: suitable
western blot: suitable

NCBI-Hinterlegungsnummer

NP_001926.1

UniProt-Hinterlegungsnummer

P27487

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... DPP4(1803)

Allgemeine Beschreibung

Dipeptidyl peptidase-4 (DPP4) is a serine type protease is also known as CD26 or adenosine deaminase binding protein. It is expressed in the plasma membranes of T cells and activated natural killer or B cells. Its expressions also have been found on a number of endothelial and differentiated epithelial cells.

Immunogen

Immunogen Sequence: GI # 4503367, sequence 547-610

Recombinant dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2)

Anwendung

Anti-DPP4 antibody produced in chicken is suitable for immunocytochemistry and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem./physiol. Wirkung

Dipeptidyl peptidase-4 (DPP4) is a protein encoded by the DPP4 gene in humans. The T cell activation molecule DPP4 is associated with a 43kDa protein. It is associated with multiple sclerosis (MS) pathophysiology. DPP4 interacts on the T cell surface along with adenosine deaminase (ADA). Mutation in DPP4 causes an X-linked Simpson-Golabi-Behmel syndrome.

Physikalische Form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?

Try our Produkt-Auswahlhilfe.

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Molecular characterization of dipeptidyl peptidase activity in serum: soluble CD26/dipeptidyl peptidase IV is responsible for the release of X-Pro dipeptides.

C Durinx et al.

European journal of biochemistry, 267(17), 5608-5613 (2000-08-22)

Dipeptidyl peptidase IV (DPPIV, EC 3.4.14.5) is a serine type protease with an important modulatory activity on a number of chemokines, neuropeptides and peptide hormones. It is also known as CD26 or adenosine deaminase (ADA; EC 3.5.4.4) binding protein. DPPIV

Direct association of adenosine deaminase with a T cell activation antigen, CD26.

J Kameoka et al.

Science (New York, N.Y.), 261(5120), 466-469 (1993-07-23)

CD26, the T cell activation molecule dipeptidyl peptidase IV (DPPIV), associates with a 43-kilodalton protein. Amino acid sequence analysis and immunoprecipitation studies demonstrated that this 43-kilodalton protein was adenosine deaminase (ADA). ADA was coexpressed with CD26 on the Jurkat T

The Simpson-Golabi-Behmel syndrome causative glypican-3, binds to and inhibits the dipeptidyl peptidase activity of CD26.

Jamshid Davoodi et al.

Proteomics, 7(13), 2300-2310 (2007-06-06)

Simpson-Golabi-Behmel syndrome (SGBS) is an X-linked condition shown to be the result of deletions of the glypican-3 (GPC3) gene. GPC3 is a proteoglycan localized to the cell membrane via a glycosylphosphatidyl-inositol (GPI) anchor. To further elucidate the GPC3 function(s), we

Low DPP4 expression and activity in multiple sclerosis.

Marta Tejera-Alhambra et al.

Clinical immunology (Orlando, Fla.), 150(2), 170-183 (2014-01-15)

Multiple sclerosis (MS) is a prototypic Th1/Th17 chronic autoimmune disease of the central nervous system. Dipeptidyl peptidase 4 (DPP4 or CD26) is a multifunctional molecule involved in autoimmune diseases' pathophysiology. We sought to integrate disparate pieces of data and analyze

Searching for an ideal vaccine candidate among different MERS coronavirus receptor-binding fragments--the importance of immunofocusing in subunit vaccine design.

Cuiqing Ma et al.

Vaccine, 32(46), 6170-6176 (2014-09-23)

The newly emerged Middle East respiratory syndrome coronavirus (MERS-CoV) is currently spreading among humans, making development of effective MERS vaccines a high priority. A defined receptor-binding domain (RBD) in MERS-CoV spike protein can potentially serve as a subunit vaccine candidate

Alle zugehörigen Dokumente anzeigen

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.