C4991

Kephalomannin

≥97% (HPLC), solid

• Synonym(e): NSC 318735
• Empirische Formel (Hill-System): C₄₅H₅₃NO₁₄
• CAS-Nummer: 71610-00-9
• Molekulargewicht: 831.90
• MDL-Nummer: MFCD01075131
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24724441
• NACRES: NA.77

Eigenschaften

• Assay: ≥97% (HPLC)
• Form: solid
• Löslichkeit: DMSO: soluble 14 mg/mL
• Wirkungsspektrum von Antibiotika: neoplastics
• Wirkungsweise: DNA synthesis | interferes
• Lagertemp.: room temp
• SMILES String: C\C=C(/C)C(=O)N[C@H]([C@@H](O)C(=O)O[C@H]1C[C@@]2(O)[C@@H](OC(=O)c3ccccc3)C4[C@@](C)([C@@H](O)C[C@H]5OC[C@@]45OC(C)=O)C(=O)[C@H](OC(C)=O)C(=C1C)C2(C)C)c6ccccc6
• InChI: 1S/C45H53NO14/c1-9-23(2)39(52)46-33(27-16-12-10-13-17-27)34(50)41(54)58-29-21-45(55)38(59-40(53)28-18-14-11-15-19-28)36-43(8,30(49)20-31-44(36,22-56-31)60-26(5)48)37(51)35(57-25(4)47)32(24(29)3)42(45,6)7/h9-19,29-31,33-36,38,49-50,55H,20-22H2,1-8H3,(H,46,52)/b23-9+/t29-,30-,31+,33-,34+,35+,36?,38-,43+,44-,45+/m0/s1
• InChIKey: DBXFAPJCZABTDR-UJLUYDJNSA-N

Beschreibung

Allgemeine Beschreibung

Chemical structure: ß-lactam

Anwendung

Cephalomannine has been used for the identification of fungal taxol (anti-cancer drug) in liquid culture.

Biochem./physiol. Wirkung

Cephalomannine is isolated from Taxus wallichiana, and serves as an antifungal agent.

Cephalomannine is a taxol derivative with antitumor, antiproliferative properties.

Sicherheitshinweise

• Piktogramme: GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H315,H318,H335
• P-Sätze: P280 - P302 + P352 - P305 + P351 + P338 + P310
• Gefahreneinstufungen: Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)