B1651

Bradykinin Fragment 1-7

≥97% (HPLC)

• Synonym(e): 1-7-Bradykinin
• Empirische Formel (Hill-System): C₃₅H₅₂N₁₀O₉
• CAS-Nummer: 23815-87-4
• Molekulargewicht: 756.85
• MDL-Nummer: MFCD00076262
• UNSPSC-Code: 12352209
• PubChem Substanz-ID: 24891606
• NACRES: NA.26

Eigenschaften

• product name: Bradykinin Fragment 1-7, ≥97% (HPLC)
• Qualitätsniveau: 200
• Assay: ≥97% (HPLC)
• Form: powder
• Farbe: white
• UniProt-Hinterlegungsnummer: P01161
• Lagertemp.: −20°C
• SMILES String: NC(CCCNC(N)=N)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NCC(=O)NC(Cc3ccccc3)C(=O)NC(CO)C(=O)N4CCCC4C(O)=O
• InChI: 1S/C35H52N10O9/c36-22(10-4-14-39-35(37)38)31(50)44-16-6-12-26(44)33(52)43-15-5-11-25(43)30(49)40-19-28(47)41-23(18-21-8-2-1-3-9-21)29(48)42-24(20-46)32(51)45-17-7-13-27(45)34(53)54/h1-3,8-9,22-27,46H,4-7,10-20,36H2,(H,40,49)(H,41,47)(H,42,48)(H,53,54)(H4,37,38,39)
• InChIKey: CRROPKNGCGVIOG-UHFFFAOYSA-N
• Angaben zum Gen: rat ... Nppa(24602)

Beschreibung

Amino Acid Sequence

Arg-Pro-Pro-Gly-Phe-Ser-Pro

Allgemeine Beschreibung

Bradykinin fragment 1-7 (BK-(1-7)), an endogenous peptide, is present in plasma.

Anwendung

Bradykinin Fragment 1-7 has been used as an external calibrant/standard in the matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) analysis of protein spots.

Bradykinin Fragment 1-7 is used in research on the specificity and kinetics of kininase(s).

Biochem./physiol. Wirkung

Bradykinin (BK) is a pro-inflammatory mediator and a neuromediator. It modulates several vascular and renal functions. Bradykinin (BK) plays a key role in inducing vascular permeability and mitogenesis. It helps to activate the liberation of nitric oxide in inflammatory and cancer tissues.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)