A7505

1,4-Androstadien-3,17-dion

• Synonym(e): 1-Dehydroandrostenedione, Androstadienedione
• Empirische Formel (Hill-System): C₁₉H₂₄O₂
• CAS-Nummer: 897-06-3
• Molekulargewicht: 284.39
• EG-Nummer: 212-977-2
• MDL-Nummer: MFCD00003614
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 24891245
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: synthetic (organic)
• Assay: ≥85% (HPLC)
• Form: powder
• Arzneimittelkontrolle: USDEA Schedule IIIN; regulated under CDSA - not available from Sigma-Aldrich Canada
• Löslichkeit: chloroform: 50 mg/mL, clear, colorless to faintly yellow
• Lagertemp.: room temp
• SMILES String: [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])CC[C@]4(C)C(=O)CC[C@@]24[H]
• InChI: 1S/C19H24O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h7,9,11,14-16H,3-6,8,10H2,1-2H3/t14-,15-,16-,18-,19-/m0/s1
• InChIKey: LUJVUUWNAPIQQI-QAGGRKNESA-N
• Angaben zum Gen: human ... CYP19A1(1588)

Beschreibung

Allgemeine Beschreibung

1,4-Androstadiene-3,17-dione is a 17-keto anabolic steroid.

Biochem./physiol. Wirkung

1,4-Androstadiene-3,17-dione is a prohormone that converts to an active steroid through the 17bHSD enzyme. 1,4-Androstadiene-3,17-dione is a metabolite of progesterone.

1,4-Androstadiene-3,17-dione is useful in forming pharmaceutically important steroids. Regio- and stereospecific hydroxylation of 1,4-androstadiene-3,17-dione increases its biological activity. Its derivative is also used to produce high-value bile acids. 1,4-Androstadiene-3,17-dione serves as a precursor for the synthesis of progesterone, testosterone, cortisol, estradiol, cortisone, prednisolone, and prednisone.