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A6226

Sigma-Aldrich

AM251

>98% (HPLC), solid, cannabinoid receptor (CB1) antagonist

Synonym(e):

1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide

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About This Item

Empirische Formel (Hill-System):
C22H21N4OCl2I
CAS-Nummer:
183232-66-8
Molekulargewicht:
555.24
MDL-Nummer:
MFCD01861181
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24891069
NACRES:
NA.77

product name

AM251, >98% (HPLC), solid

Qualitätsniveau

100

Assay

>98% (HPLC)

Form

solid

Farbe

white

Löslichkeit

DMSO: >10 mg/mL
H2O: insoluble

Ersteller

Sanofi Aventis

SMILES String

Cc1c(nn(-c2ccc(Cl)cc2Cl)c1-c3ccc(I)cc3)C(=O)NN4CCCCC4

InChI

1S/C22H21Cl2IN4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-7-16(23)13-18(19)24)21(14)15-5-8-17(25)9-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)

InChIKey

BUZAJRPLUGXRAB-UHFFFAOYSA-N

Angaben zum Gen

mouse ... Cnr1(12801) , Cnr2(12802)
rat ... Cnr1(25248)

Anwendung

AM251, a CB1 cannabinoid receptor antagonist, has been used in a study to determine its interaction with hippocampal neurons to enhance spatial memory in mice.

Biochem./physiol. Wirkung

AM251 is a CB1 cannabinoid receptor antagonist.

Leistungsmerkmale und Vorteile

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sonstige Hinweise

Salt content may vary.

H-Sätze

H413

P-Sätze

P273 - P501

Gefahreneinstufungen

Aquatic Chronic 4

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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