SMB00953

2-Cyano-3,3-diphenylacrylic acid

≥95%

• Synonym(e): α-Cyano-β-diphenylacrylic acid, 2-Cyano-3,3-diphenylpropenoic acid
• Empirische Formel (Hill-System): C₁₆H₁₁NO₂
• CAS-Nummer: 10380-41-3
• Molekulargewicht: 249.26
• UNSPSC-Code: 12352106
• NACRES: NA.22

Eigenschaften

• Biologische Quelle: synthetic
• Qualitätsniveau: 200
• Assay: ≥95%
• Form: solid
• Mol-Gew.: 249.26 g/mol
• Lagerbedingungen: (Tightly closed. Dry.)
• Methode(n): HPLC: suitable
• Farbe: white to off-white
• Lagertemp.: 2-8°C
• InChI: 1S/C16H11NO2/c17-11-14(16(18)19)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10H,(H,18,19)
• InChIKey: VSXIZXFGQGKZQG-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

2-Cyano-3,3-diphenylacrylic acid (CDA) belongs to the class of α,β-unsaturated carboxylic acids. It is a primary metabolite of Octocrylene, an organic sunscreen that functions by absorbing UVB radiation and short UVA wavelengths, commonly utilized in cosmetics for sun protection. CDA exhibits prolonged systemic availability after dermal exposure which may accumulate in the body. It can be used to study skin-permeable selective cyclooxygenaswe-2 inhibitor composition, and to study hydrophilic components of cosmetic compositions, such as in sunscreen.

Anwendung

2-Cyano-.3-diphenylacrylic acid finds application in metabolomics, cosmetics and cancer research

Biochem./physiol. Wirkung

Within the human body, Octocrylene, a non-polar compound, undergoes metabolism to become a water-soluble metabolite 2-cyano-3,3-diphenylacrylic acid, which is excreted through the kidneys. A pilot study in the general population has consistently detected CDAA, and its levels have been linked to recent sunscreen application.

Leistungsmerkmale und Vorteile

• High quality compound suitable for multiple research applications
• Compatible with a wide variety of chromatographic and spectrometry techniques

Sonstige Hinweise

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This product is intended for research purposes only, and it is not meant for human consumption.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable