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Merck

MAB2120Z

Sigma-Aldrich

Anti-NCAM Antibody, extracellular, clone ERIC-1, Azide free

clone ERIC-1, Chemicon®, from mouse

Synonym(e):

NeuralCellAdhesionMolecule, CD56, MAB2120

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

ERIC-1, monoclonal

Speziesreaktivität

human, pig

Hersteller/Markenname

Chemicon®

Methode(n)

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

Isotyp

IgG1

Eignung

not suitable for flow cytometry

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... NCAM1(4684)

Allgemeine Beschreibung

The previously assigned protein identifier P13592 has been merged into P13591. Full details can be found on the UniProt database.

Spezifität

Recognizes N-CAM expressed on developing and adult neuroectrodermal tissues in Humans. Neuroectodermal tumors also stain including Elioma, ependymoma, neuroblastoma, medulloblastoma, retinoblastoma and teratoma. Oat cell carcinoma and Wilms tumor are also highly reactive. Will react on Natural Killer cells. Recognizes 120, 140 and 180 kDa NCAM isoforms.

Immunogen

Epitope: extracellular
Human Retinoblastoma tumor

Anwendung

Research Category
Neurowissenschaft
Research Sub Category
Wachstumskegel & Axonlenkung

Neurofilament & Neuronen-Stoffwechsel
Anti-NCAM Antibody, extracellular, clone ERIC-1, Azide free is an antibody against NCAM for use in ELISA, WB, IH.
Immunohistology on frozen tissue sections acetone fixation only.

Immunoblotting: Recognizes 120, 140, and 180 kDa NCAM isoforms.

ELISA: 80 ng/mL

Does not work in flow cytometry.

Optimal working dilutions must be determined by end user.

Verlinkung

Replaces: MAB2122

Physikalische Form

Format: Purified
Liquid in PBS. Does not contain any preservatives

Lagerung und Haltbarkeit

Store at -20°C only. Avoid repeated freeze-thaw cycles.

Hinweis zur Analyse

Control
Recommended positive control tissue: Neuroblastoma

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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GDNF family ligands trigger indirect neuroprotective signaling in retinal glial cells.
Hauck, SM; Kinkl, N; Deeg, CA; Swiatek-de Lange, M; Schoffmann, S; Ueffing, M
Molecular and cellular biology null
Priyadarsini Kumar et al.
PloS one, 10(8), e0135089-e0135089 (2015-08-13)
Trophoblast differentiation during early placental development is critical for successful pregnancy and aberrant differentiation causes preeclampsia and early pregnancy loss. During the first trimester, cytotrophoblasts are exposed to low oxygen tension (equivalent to~2%-3% O2) and differentiation proceeds along an extravillous

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