ECM440
β Integrin Screening Kit
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About This Item
UNSPSC-Code:
12161503
eCl@ss:
32161000
NACRES:
NA.41
Empfohlene Produkte
Speziesreaktivität
human
Qualitätsniveau
Hersteller/Markenname
Chemicon®
Methode(n)
ELISA: suitable
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
Versandbedingung
dry ice
Allgemeine Beschreibung
Chemicon Investigator Kits for Integrin Research are a cost-effective source of reagents for all investigators involved with this expanding field of study. The b Integrin Screening Investigator Kit is designed for the screening of beta integrin family members.
Integrins belong to a large family of cell surface proteins commonly referred to as glycoproteins. Integrins are composed of noncovalently associated alpha and beta subunits which make up heterodimers: the larger termed alpha chain and the smaller beta chain. At least 16 alpha subunits and 8 beta subunits are expressed, which can give rise to 22 different integrins. Integrins are thought to play critical roles in cell migration, differentiation, and survival. There is now considerable evidence that these transmembrane receptors play an important role in the regulation of gene expression and signal transduction. Excellent reviews of integrin structure, function, and ligand specificity may be found in: Hynes, R. 1992. Cell 69:11-25; Kramer, R. 1993. "Integrin Structure and Ligand Specificity in Cell-Matrix Interactions" in Molecular and Cellular Aspects of Basement Membranes. Academic Press.
Chemicon offers the Beta Integrin Screening Investigator Kit for studies of human beta integrin subunits. All kit reagents are also available in larger sizes. The reagents in this kit are not application specific but rather may be used in a variety of procedures, depending upon the needs of the individual investigator.
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Integrins belong to a large family of cell surface proteins commonly referred to as glycoproteins. Integrins are composed of noncovalently associated alpha and beta subunits which make up heterodimers: the larger termed alpha chain and the smaller beta chain. At least 16 alpha subunits and 8 beta subunits are expressed, which can give rise to 22 different integrins. Integrins are thought to play critical roles in cell migration, differentiation, and survival. There is now considerable evidence that these transmembrane receptors play an important role in the regulation of gene expression and signal transduction. Excellent reviews of integrin structure, function, and ligand specificity may be found in: Hynes, R. 1992. Cell 69:11-25; Kramer, R. 1993. "Integrin Structure and Ligand Specificity in Cell-Matrix Interactions" in Molecular and Cellular Aspects of Basement Membranes. Academic Press.
Chemicon offers the Beta Integrin Screening Investigator Kit for studies of human beta integrin subunits. All kit reagents are also available in larger sizes. The reagents in this kit are not application specific but rather may be used in a variety of procedures, depending upon the needs of the individual investigator.
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Anwendung
Research Category
Zellstruktur
Zellstruktur
Research Sub Category
Integrine
Integrine
Komponenten
beta1 Mouse Monoclonal Antibody (Part No. MAB1951Z-20)- 1 tube, 20 μg.
beta2 Mouse Monoclonal Antibody (Part No. MAB1962Z-20)- 1 tube, 20 μg.
beta3 Mouse Monoclonal Antibody (Part No. MAB1957Z-20)- 1 tube, 20 μg.
beta4 Mouse Monoclonal Antibody (Part No. MAB2060-20)- 1 tube, 20 μg.
beta5 Rabbit Polyclonal Antibody (Part No. AB1926-20)- 1 tube, 20 μL.
beta2 Mouse Monoclonal Antibody (Part No. MAB1962Z-20)- 1 tube, 20 μg.
beta3 Mouse Monoclonal Antibody (Part No. MAB1957Z-20)- 1 tube, 20 μg.
beta4 Mouse Monoclonal Antibody (Part No. MAB2060-20)- 1 tube, 20 μg.
beta5 Rabbit Polyclonal Antibody (Part No. AB1926-20)- 1 tube, 20 μL.
Physikalische Form
Chemicon′s Beta Integrin Screening Kit (ECM440) contains monoclonals to beta1, beta2, beta3, beta4, and polyclonal beta5. 20 μg of each monoclonal and 20 μL of polyclonal is included in this economical kit. All components may also be purchased in larger sizes.
Lagerung und Haltbarkeit
Store antibodies at -20°C.
Important Note: Due to the small volumes contained within the kit, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge before opening to dislodge any liquid entrapped in the container′s cap during shipment.
Important Note: Due to the small volumes contained within the kit, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge before opening to dislodge any liquid entrapped in the container′s cap during shipment.
Rechtliche Hinweise
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Lagerklassenschlüssel
10 - Combustible liquids
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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