ABE1007

Anti-BATF3 Antibody

from rabbit, purified by affinity chromatography

• Synonym(e): Basic leucine zipper transcriptional factor ATF-like 3, B-ATF-3, 21 kDa small nuclear factor isolated from T-cells, Jun dimerization protein p21SNFT
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Aufgereinigt durch: affinity chromatography
• Speziesreaktivität: human
• Methode(n): flow cytometry: suitable; western blot: suitable
• NCBI-Hinterlegungsnummer: NP_061134
• UniProt-Hinterlegungsnummer: Q9NR55
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... BATF3(55509)

Beschreibung

Allgemeine Beschreibung

BATF3, also known as Basic leucine zipper transcriptional factor ATF-like 3, B-ATF-3, 21 kDa small nuclear factor isolated from T-cells, or Jun dimerization protein p21SNFT, and encoded by the gene BATF3/SNFT, is an AP-1 family transcription factor that controls the differentiation of CD8+ thymic conventional dendritic cells in the immune system. BATF3 is required for the development of CD8-alpha+ classical dendritic cells (cDCs) and related CD103+ dendritic cells that cross-present antigens to CD8. BATF3 acts via the formation of a heterodimer with JUN family proteins that recognizes and bind the DNA sequence 5′-TGA[CG]TCA-3′ and thus regulates the expression of the target genes. BATF3 is localized to the nucleus. BATF3 is expressed in myeloid dendritic cells and T cell precursor immune cells primarily.

Immunogen

Epitope: Leucine-zipper

KLH-conjugated linear peptide corresponding to the Leucine-zipper of human BATF3.

Anwendung

Research Category
Epigenetik & nukleäre Funktionen

Detect BATF3 using this Anti-BATF3 antibody validated for use in western blotting & flow cytometry.

Flow Cytometry Analysis: 1 µg of this antibody detected BATF3 in human PBMC cells.

Research Sub Category
Nuclear Receptors

Qualität

Evaluated by Western Blotting in human spleen tissue lysate.

Western Blotting Analysis: 0.25 µg/mL of this antibody detected BATF3 in 10 µg of human spleen tissue lysate.

Zielbeschreibung

~17 kDa observed

Physikalische Form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable