538909

Prostaglandin D₂

Major prostaglandin metabolite in brain and an important inflammatory mediator in mast cells.

• Synonym(e): Prostaglandin D₂, PGD₂
• Empirische Formel (Hill-System): C₂₀H₃₂O₅
• CAS-Nummer: 41598-07-6
• Molekulargewicht: 352.47
• MDL-Nummer: MFCD00077857
• UNSPSC-Code: 12352211
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze
• Farbe: white
• Löslichkeit: ethanol: 100 mg/mL; acetone: soluble; ethyl acetate: soluble; methanol: soluble
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• InChI: 1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-/m0/s1
• InChIKey: BHMBVRSPMRCCGG-OUTUXVNYSA-N

Beschreibung

Allgemeine Beschreibung

Major prostaglandin metabolite in the brain and an important inflammatory mediator in mast cells. Neuromodulator that evokes nerve-mediated Cl^- secretion. Stimulates adenylate cyclase.

Biochem./physiol. Wirkung

Cell permeable: no

Primary Target
Adenylate cyclase

Product does not compete with ATP.

Reversible: no

Warnhinweis

Toxicity: Harmful (C)

Rekonstituierung

Following reconstitution, aliquot and freeze (-20°C).

Sonstige Hinweise

Horn, E.H., et al. 1995. Clin. Sci. 89, 91.
Frieling, T., et al. 1994. Am. J. Physiol. 266, G132.
Huttemeier, P.C., et al. 1993. Prostaglandins 45, 177.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Danger
• H-Sätze: H302,H360
• P-Sätze: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Gefahreneinstufungen: Acute Tox. 4 Oral - Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable