O-008

Oxycodon-D₆ -Lösung

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirische Formel (Hill-System): C₁₈H₁₅NO₄D₆
• CAS-Nummer: 152477-91-3
• Molekulargewicht: 321.40
• EG-Nummer: 200-659-6
• MDL-Nummer: MFCD00673304
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329818817
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material
• Qualitätsniveau: 300
• Form: liquid
• Leistungsmerkmale: Snap-N-Spike^®/Snap-N-Shoot^®
• Verpackung: ampule of 1 mL
• Hersteller/Markenname: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• Konzentration: 1.0 mg/mL in methanol
• Methode(n): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Anwendung(en): forensics and toxicology
• Format: single component solution
• Lagertemp.: 2-8°C
• SMILES String: [2H]C([2H])([2H])Oc1ccc2C[C@H]3N(CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O)C([2H])([2H])[2H]
• InChI: 1S/C18H21NO4/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10/h3-4,13,16,21H,5-9H2,1-2H3/t13-,16+,17+,18-/m1/s1/i1D3,2D3
• InChIKey: BRUQQQPBMZOVGD-UKHJWGAOSA-N

Beschreibung

Allgemeine Beschreibung

Ein als stabil gekennzeichneter interner Standard, der sich für die Quantifizierung des Oxycodon-Gehalts in Urin, Serum oder Plasma mittels LC/MS oder GC/MS in der Urin-Drogenkontrolle, klinischen Toxikologie, forensischen Analytik oder für Isotopenverdünnungsmethoden eignet. Oxycodon ist ein halbsynthetisches Opioid-Analgetikum, das unter vielen Handelsnamen, einschließlich OxyContin^® und Percocet^®, zur Behandlung von mittelschweren bis schweren Schmerzen verkauft wird. Oxycodon wird außerdem illegal unter Bezeichnungen wie „Roxies“, „Blues“ und „Perks“ verkauft.

Anwendung

• Oxycodone-D₆ as an isotopic standard: Oxycodone-D₆ is employed extensively as a high-quality isotopic standard in analytical chemistry, particularly in mass spectrometry. This application is crucial for ensuring accuracy and precision in the quantification of oxycoDonein various biological matrices, enhancing drug monitoring and forensic analyses.


• Stable isotope-labeled oxycoDonefor pharmacokinetic studies: Researchers use Oxycodone-D₆ to investigate the pharmacokinetics of oxycodone, including its absorption, distribution, metabolism, and excretion. The use of this stable isotope-labeled compound allows for more precise tracking of drug metabolites, contributing significantly to the understanding of drug behavior in the human body.


• Oxycodone-D₆ in metabolite analysis: The deuterated form of oxycoDoneis critical in metabolite profiling studies. It serves as an internal standard that facilitates the identification and quantification of oxycoDonemetabolites, thereby aiding in the exploration of metabolic pathways and potential drug interactions.


• Use in analytical standard development for biochemistry research: Oxycodone-D₆ solution is integral to developing robust analytical methods for drug testing and research. Its stability and reliability make it a preferred choice for validating new analytical techniques in biochemistry labs.


• Investigation of opioid receptor binding assays: This compound is utilized in studies exploring opioid receptor interactions, aiding in the development of targeted therapies for pain management. Oxycodone-D₆ helps in understanding the binding efficiency and pharmacodynamics of opioids at the molecular level.

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

OxyContin is a registered trademark of Purdue Pharma L.P.

Percocet is a registered trademark of Endo Pharmaceuticals Inc.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS02,GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H225 - H301 + H311 + H331 - H370
• P-Sätze: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Zielorgane: Eyes
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 1
• Flammpunkt (°F): 49.5 °F - closed cup
• Flammpunkt (°C): 9.7 °C - closed cup