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84570

Sigma-Aldrich

Sarcosin-methylester -hydrochlorid

≥97.0% (T)

Synonym(e):

N-Methylglycine methyl ester hydrochloride

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About This Item

Lineare Formel:
CH3NHCH2COOCH3 · HCl
CAS-Nummer:
13515-93-0
Molekulargewicht:
139.58
Beilstein:
3619268
EG-Nummer:
236-853-2
MDL-Nummer:
MFCD00038876
UNSPSC-Code:
12352108
PubChem Substanz-ID:
57653011
NACRES:
NA.22

Qualitätsniveau

100

Assay

≥97.0% (T)

Form

powder

Eignung der Reaktion

reaction type: solution phase peptide synthesis

Verunreinigungen

≤3% sarcosine hydrochloride

mp (Schmelzpunkt)

117-119 °C (lit.)

Anwendung(en)

peptide synthesis

SMILES String

Cl.CNCC(=O)OC

InChI

1S/C4H9NO2.ClH/c1-5-3-4(6)7-2;/h5H,3H2,1-2H3;1H

InChIKey

HQZMRJBVCVYVQA-UHFFFAOYSA-N

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

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D O H Teare et al.
The journal of physical chemistry. B, 109(44), 20923-20928 (2006-07-21)
A new class of protein-resistant film based on N-substituted glycine derivatives is described. Pulsed plasma deposited poly(N-acryloylsarcosine methyl ester) coatings are shown to be resistant toward the adsorption of fibrinogen and lysozyme. Deposition and UV irradiation of the polymer through
A M Bersten et al.
Biochimica et biophysica acta, 762(3), 429-436 (1983-06-02)
The effects of competitive inhibitors of transglutaminase on the formation of myotubes by the fusion of myoblasts in vitro has been investigated. Myotube formation was inhibited when myoblasts from 11-day-old chick embryos were cultured in vitro in the presence of
M A Lindsay et al.
Bioscience reports, 10(6), 557-561 (1990-12-01)
Ca(2+)-Induced insulin release from electropermeabilised islets is inhibited by the transglutaminase inhibitors monodansylcadaverine, glycine methylester, methylamine and cystamine but not by the control compounds dimethyl monodansylcadaverine and sarcosine methylester which lack the primary amine group. Neither monodansylcadaverine nor glycine methylester
C Alarcon et al.
Bioscience reports, 5(7), 581-587 (1985-07-01)
Glycine methyl ester, an inhibitor of transglutaminase, decreased glucose-stimulated insulin release and delayed proinsulin conversion in rat pancreatic islets pulse-labelled with L-[4-3H]phenylalanine. Sarcosine methyl ester, which does not inhibit transglutaminase activity, failed to affect insulin release and proinsulin conversion. The
A Sener et al.
Endocrinology, 117(1), 237-242 (1985-07-01)
The Ca2+-responsive enzyme transglutaminase, which catalyzes the cross-bridging of proteins, is present in pancreatic islet cells, but its participation in the process of insulin release remains to be documented. Glycine methylester (1.0-10.0 mM) inhibited, in a dose-related manner, transglutaminase activity

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