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Sigma-Aldrich

Poly(ethylenglycol)methylether

average MN 10,000, methoxy, hydroxyl

Synonym(e):

Methoxy-polyethylenglykol, Polyethylenglykol-monomethylether, mPEG

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About This Item

Lineare Formel:
CH3(OCH2CH2)nOH
CAS-Nummer:
9004-74-4
MDL-Nummer:
MFCD00084416
UNSPSC-Code:
12162002
NACRES:
NA.23

product name

Poly(ethylenglycol)methylether, average Mn 10,000

Dampfdichte

>1 (vs air)

Dampfdruck

0.05 mmHg ( 20 °C)

Form

chunks
powder or crystals

Mol-Gew.

average Mn 10,000

mp (Schmelzpunkt)

60-65 °C

Mw/Mn

≤1.2

Ω-Ende

hydroxyl

α-Ende

methoxy

Lagertemp.

−20°C

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

InChIKey

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

415.0 °F - closed cup

Flammpunkt (°C)

212.80 °C - closed cup

Analysenzertifikate (COA)

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Poly(ethylenglykol) average Mn 10,000, flakes

Sigma-Aldrich

309028

Poly(ethylenglykol)

O-(2-Aminoethyl)-O′-methyl-polyethylenglykol 20,000

Sigma-Aldrich

07966

O-(2-Aminoethyl)-O′-methyl-polyethylenglykol

Poly(ethylenglykol) 10,000

Sigma-Aldrich

81280

Poly(ethylenglykol)

Robert K Delong et al.
Nanomedicine (London, England), 7(12), 1851-1862 (2012-09-05)
Nanoparticle conjugates have the potential for delivering siRNA, splice-shifting oligomers or nucleic acid vaccines, and can be applicable to anticancer therapeutics. This article compares tripartite conjugates with gold nanoparticles or synthetic methoxypoly(ethylene glycol)-block-polyamidoamine dendrimers. Interactions with model liposomes of a
Prakash G Avaji et al.
Bioorganic & medicinal chemistry letters, 23(6), 1763-1767 (2013-02-16)
Saturated fatty acids (FA) were grafted using tyrosine as a spacer group to the cyclotriphosphazene ring along with equimolar hydrophilic methoxy poly(ethylene glycol) (MPEG) in cis-nongeminal way. Seven new cyclotriphosphazene amphiphiles were prepared from combinations of hydrophilic MPEGs with different
Mulu Z Tesfay et al.
Journal of virology, 87(7), 3752-3759 (2013-01-18)
We are developing oncolytic vesicular stomatitis viruses (VSVs) for systemic treatment of multiple myeloma, an incurable malignancy of antibody-secreting plasma cells that are specifically localized in the bone marrow. One of the presumed advantages for using VSV as an oncolytic
Seung-Young Lee et al.
Biomaterials, 34(2), 552-561 (2012-10-20)
Although targeted delivery mediated by ligand modified or tumor microenvironment sensitive nanocarriers has been extensively pursued for cancer chemotherapy, the efficiency is still limited by premature drug release after systemic administration. Herein we report a highly blood-stable, tumor-adaptable drug carrier
Junming Li et al.
Journal of biomedical nanotechnology, 8(5), 809-817 (2012-08-15)
In this study, quercetin (QC) with cancer chemoprevention effect and anticancer potential was loaded into polymeric micelles of methoxy poly(ethylene glycol)-cholesterol conjugate (mPEG-Chol) in order to increase its water solubility. MPEG-Chol with lower critical micelle concentration (CMC) value (4.0 x
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Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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