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TP53

tumor protein p53

Synonyme:
BCC7, LFS1, P53, TRP53
Spezies:
Human TP53 (7157), Rat Tp53 (24842), Zebrafish tp53 (30590), Horse TP53 (100062044), domestic cat TP53 (493847), dog TP53 (403869), chicken TP53 (396200), cow TP53 (281542), sheep TP53 (443421), domestic guinea pig Tp53 (100379269) ...Mehr
UniProtKB-ID:
P04637, Q15086, Q15087, Q15088, Q16535, Q16807, Q16808, Q16809
Gen-ID:
  • Human(7157) Summary: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]
  • Rat(24842) tumor protein p53
  • Zebrafish(30590) tumor protein p53
  • Horse(100062044) tumor protein p53
  • domestic cat(493847) tumor protein p53
  • dog(403869) tumor protein p53
  • chicken(396200) tumor protein p53
  • cow(281542) tumor protein p53
  • sheep(443421) tumor protein p53
  • domestic guinea pig(100379269) tumor protein p53
  • Domestic Rabbit(100009292) tumor protein p53
  • naked mole-rat(101701769) tumor protein p53

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ELISA

Produktnummer
Beschreibung
Spezies
RAB0500
Human p53 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Spezies
human
RAB0910
Rat Tp53 / Cellular Tumor Antigen p53 ELISA Kit, ,
Spezies
rat

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
MABE339
Anti-p53(Wildtyp)-Antikörper, Klon PAb1620, clone Pab1620, from mouse,
Speziesreaktivität
human, mouse
Anwendung
immunohistochemistry
western blot
453M-9
p53 (DO7) Mouse Monoclonal Antibody, ,
Speziesreaktivität
human
Anwendung
immunohistochemistry
CBL404
Anti-p53-Antikörper, AS 211–220, Klon 240, clone PAb240, Chemicon®, from mouse,
Speziesreaktivität
bovine, chicken, hamster, human, monkey, mouse, rat
Anwendung
immunohistochemistry
immunoprecipitation (IP)
western blot
OP43
Anti-p53 (Ab-6) (Pantropic) Mouse mAb (DO-1), liquid, clone DO-1, Calbiochem®,
Speziesreaktivität
feline, human
Anwendung
SAB5702066
Anti-Acetyl-p53-K382 Antibody, clone 0, Rabbit Monoclonal, ,
Speziesreaktivität
mouse
Anwendung

Cell Lines

Produktnummer
Beschreibung
Spezies
CLLS1049
MCF10A CELLS TP53 (-/-), ,
Spezies
human
CLLS1007
SW48 Cells TP53 -/-, ,
Spezies
human
CLLS1127
DLD1 Cells TP53 -/-, ,
Spezies
human

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
PZ0115
CP-31398 dihydrochloride hydrate, ≥98% (HPLC),
Spezies
mouse, rat, human

Proteins

Produktnummer
Beschreibung
Spezies
23-034-M
p53-Protein, 10 µg, Full length, recombinant human p53. N-terminal c-Myc, 6His-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.,
Spezies
P6374
p53 human, recombinant, expressed in baculovirus infected Sf21 cells,
Spezies
human
P6249
p53 human, recombinant, expressed in E. coli, buffered aqueous glycerol solution,
Spezies
human
14-865
p53-GST (recombinant protein), ,
Spezies
SRP2108
p53 (1-81), mutant, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
EHU123221
MISSION® esiRNA, targeting human TP53,
Spezies
human