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SPO11

SPO11 meiotic protein covalently bound to DSB

Synonyme:
CT35, SPATA43, TOPVIA
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(23626) Summary: Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described. [provided by RefSeq, Jul 2008]
  • Mouse(26972) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
  • Rat(366261) SPO11 meiotic protein covalently bound to DSB
  • Zebrafish(402982) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
  • chicken(768915) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
  • domestic cat(101090003) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
  • Horse(100050365) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
  • dog(610247) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
  • cow(524105) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
  • sheep(101118122) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
  • Domestic Rabbit(100359270) SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
  • naked mole-rat(101706565) SPO11 meiotic protein covalently bound to DSB
  • domestic guinea pig(100725083) SPO11 meiotic protein covalently bound to DSB

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-SPO11 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
bovine, dog, guinea pig, human, rat
Anwendung
western blot
Anti-SPO11 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
western blot