SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
Synonyme:
NCX1
Spezies:
Human SLC8A1 (6546), Mouse Slc8a1 (20541), Rat Slc8a1 (29715), Domestic Rabbit SLC8A1 (100328570), naked mole-rat Slc8a1 (101711105), domestic guinea pig Slc8a1 (100135620), cow SLC8A1 (337925), sheep SLC8A1 (101116716), chicken SLC8A1 (395760), dog SLC8A1 (475738) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(6546) Summary: In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.[supplied by OMIM, Apr 2004]
- Mouse(20541) solute carrier family 8 (sodium/calcium exchanger), member 1
- Rat(29715) solute carrier family 8 (sodium/calcium exchanger), member 1
- Domestic Rabbit(100328570) solute carrier family 8 (sodium/calcium exchanger), member 1
- naked mole-rat(101711105) solute carrier family 8 (sodium/calcium exchanger), member 1
- domestic guinea pig(100135620) solute carrier family 8 (sodium/calcium exchanger), member 1
- cow(337925) solute carrier family 8 (sodium/calcium exchanger), member 1
- sheep(101116716) solute carrier family 8 (sodium/calcium exchanger), member 1
- chicken(395760) solute carrier family 8 (sodium/calcium exchanger), member 1
- dog(475738) solute carrier family 8 (sodium/calcium exchanger), member 1
- Horse(100034157) solute carrier family 8 (sodium/calcium exchanger), member 1
- domestic cat(493807) solute carrier family 8 (sodium/calcium exchanger), member 1
- dog(493808) solute carrier family 8 (sodium/calcium exchanger), member 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
ANTI-SLC8A1 (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Speziesreaktivität
human, mouse
Anwendung
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Natrium-Calcium-Austauscher 1-Antikörper, Chemicon®, from rabbit,
Speziesreaktivität
rat
Anwendung
ELISA
western blot
western blot
Monoclonal Anti-Na+/Ca2+ Exchanger antibody produced in mouse, clone C2C12,
Speziesreaktivität
canine, guinea pig, human, rabbit, rat
Anwendung
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-SLC8A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence