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SELPLG

selectin P ligand

Synonyme:
CD162, CLA, PSGL-1, PSGL1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(6404) Summary: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
  • Mouse(20345) selectin, platelet (p-selectin) ligand
  • Rat(363930) selectin P ligand
  • cow(617434) selectin P ligand
  • sheep(101102589) selectin P ligand
  • naked mole-rat(101713908) selectin P ligand
  • domestic guinea pig(100712957) selectin P ligand
  • Zebrafish(100884146) selectin P ligand
  • chicken(772212) selectin P ligand
  • dog(611673) selectin P ligand
  • Horse(100034025) selectin P ligand
  • domestic cat(101087945) selectin P ligand

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ELISA

Produktnummer
Beschreibung
Spezies
Human PSGL-1 ELISA, for serum, plasma and cell culture supernatants,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-PSGL-1/CD162 Antibody, clone KPL-1 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human
Anwendung
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-P-Selectin Glycoprotein Ligand-1 Antibody, clone KPL-1, clone KPL-1, Chemicon®, from mouse,
Speziesreaktivität
human
Anwendung
flow cytometry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-PSGL-1/CD162 Antibody, clone HECA-452, ,
Speziesreaktivität
human
Anwendung
flow cytometry
immunohistochemistry

western blot
Monoclonal Anti-CD162-APC antibody produced in mouse, clone TC2,
Speziesreaktivität
Anwendung
flow cytometry
Anti-SELPLG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human SELPLG,
Spezies
human
MISSION® esiRNA, targeting mouse Selplg,
Spezies
mouse