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Merck

PRKDC

protein kinase, DNA-activated, catalytic polypeptide

Synonyme:
DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350
Spezies:
Human PRKDC (5591), Mouse Prkdc (19090), Rat Prkdc (360748), chicken PRKDC (395376), dog PRKDC (474176), domestic cat PRKDC (101088389), naked mole-rat Prkdc (101722248), Domestic Rabbit PRKDC (100125348), domestic guinea pig Prkdc (100724826), cow PRKDC (512740)
UniProtKB-ID:
P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6
Gen-ID:
  • Human(5591) Summary: This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010]
  • Mouse(19090) protein kinase, DNA activated, catalytic polypeptide
  • Rat(360748) protein kinase, DNA activated, catalytic polypeptide
  • chicken(395376) protein kinase, DNA-activated, catalytic polypeptide
  • dog(474176) protein kinase, DNA-activated, catalytic polypeptide
  • domestic cat(101088389) protein kinase, DNA-activated, catalytic polypeptide
  • naked mole-rat(101722248) protein kinase, DNA-activated, catalytic polypeptide
  • Domestic Rabbit(100125348) protein kinase, DNA-activated, catalytic polypeptide
  • domestic guinea pig(100724826) protein kinase, DNA-activated, catalytic polypeptide
  • cow(512740) protein kinase, DNA-activated, catalytic polypeptide
  • sheep(101111377) protein kinase, DNA-activated, catalytic polypeptide

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
SAB4300443
Anti-PRKDC (Ab-2609) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
western blot
SAB4504169
Anti-phospho-DNA-PK (pSer2056) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry
NA57
Anti-DNA-PK (Ab-2) Mouse mAb (18-2), liquid, clone 18-2, Calbiochem®,
Speziesreaktivität
human
Anwendung
HPA035174
Anti-PRKDC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
SAB4502383
Anti-DNA-PK antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse
Anwendung
ELISA
immunofluorescence

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
N5757
α-Naphthoflavon, ≥98%,
Spezies
human, rat

esiRNA

Produktnummer
Beschreibung
Spezies
EHU123791
MISSION® esiRNA, targeting human PRKDC,
Spezies
human
EMU005241
MISSION® esiRNA, targeting mouse Prkdc,
Spezies
mouse