MYLK
myosin light chain kinase
Synonyme:
AAT7, KRP, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, MYLK1, smMLCK
Spezies:
Human MYLK (4638), Mouse Mylk (107589), Rat Mylk (288057), chicken MYLK (396445), dog MYLK (488012), Horse MYLK (100070482), cow MYLK (338037), naked mole-rat Mylk (101704236), Domestic Rabbit MYLK (100009143), domestic guinea pig Mylk (100714177)
UniProtKB-ID:
Gen-ID:
- Human(4638) Summary: This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008]
- Mouse(107589) myosin, light polypeptide kinase
- Rat(288057) myosin light chain kinase
- chicken(396445) myosin light chain kinase
- dog(488012) myosin light chain kinase
- Horse(100070482) myosin light chain kinase
- cow(338037) myosin light chain kinase
- naked mole-rat(101704236) myosin light chain kinase
- Domestic Rabbit(100009143) myosin light chain kinase
- domestic guinea pig(100714177) myosin light chain kinase
- sheep(443334) myosin light chain kinase
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Monoclonal Anti-Myosin Light Chain Kinase antibody produced in mouse, clone K36, ascites fluid,
Speziesreaktivität
avian, mammals
Anwendung
immunoprecipitation (IP)
microarray
western blot
microarray
western blot
Anti-MYLK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
western blot
Anti-MYLK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
Anti-MYLK antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human, mouse
Anwendung
ELISA
western blot
western blot
Anti-MYLK Antibody, clone 1J2U2, Rabbit Monoclonal, ,
Speziesreaktivität
human, rat
Anwendung
western blot
Small Molecule - Inhibitor
Produktnummer
Beschreibung
Spezies
Proteins
Produktnummer
Beschreibung
Spezies
MLCK Protein, active, 10 µg, Active, N-terminal 6His-tagged, recombinant, human MLCK, amino acids 1425-1771, for use in Kinase Assays.,
Spezies
human
MLCK (1425-1776), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human