KDR

kinase insert domain receptor (a type III receptor tyrosine kinase)

Synonyme:

CD309, FLK1, VEGFR, VEGFR2

Spezies:

Human KDR (3791), Mouse Kdr (16542), Rat Kdr (25589), Goat KDR (100860836), sheep KDR (443087), Domestic Rabbit KDR (100008607), domestic guinea pig Kdr (100726761), naked mole-rat Kdr (101726029), Zebrafish kdr (554230), cow KDR (407170) ...Mehr

UniProtKB-ID:

P35968, A2RRS0, B5A925, C5IFA0, O60723, Q14178

Gen-ID:

Human(3791) Summary: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
Mouse(16542) kinase insert domain protein receptor
Rat(25589) kinase insert domain receptor
Goat(100860836) kinase insert domain receptor (a type III receptor tyrosine kinase)
sheep(443087) vascular endothelial growth factor receptor-2
Domestic Rabbit(100008607) kinase insert domain receptor (a type III receptor tyrosine kinase)
domestic guinea pig(100726761) kinase insert domain receptor (a type III receptor tyrosine kinase)
naked mole-rat(101726029) kinase insert domain receptor (a type III receptor tyrosine kinase)
Zebrafish(554230) kinase insert domain receptor (a type III receptor tyrosine kinase)
cow(407170) kinase insert domain receptor (a type III receptor tyrosine kinase)
Horse(100033959) kinase insert domain receptor (a type III receptor tyrosine kinase)
domestic cat(101090260) kinase insert domain receptor (a type III receptor tyrosine kinase)
dog(482154) kinase insert domain receptor (a type III receptor tyrosine kinase)
chicken(395323) kinase insert domain receptor (a type III receptor tyrosine kinase)
Thale Cress(839585) basic helix-loop-helix protein KIDARI

Produkte (45)
Peer-Reviewed-Artikel (773)

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