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CHUK

conserved helix-loop-helix ubiquitous kinase

Synonyme:
IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(1147) Summary: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
  • Mouse(12675) conserved helix-loop-helix ubiquitous kinase
  • Rat(309361) conserved helix-loop-helix ubiquitous kinase
  • Zebrafish(393287) conserved helix-loop-helix ubiquitous kinase
  • cow(281073) conserved helix-loop-helix ubiquitous kinase
  • Horse(100070393) conserved helix-loop-helix ubiquitous kinase
  • dog(477796) conserved helix-loop-helix ubiquitous kinase
  • chicken(423669) conserved helix-loop-helix ubiquitous kinase
  • domestic cat(101095617) conserved helix-loop-helix ubiquitous kinase
  • sheep(101111143) conserved helix-loop-helix ubiquitous kinase
  • domestic guinea pig(100726357) conserved helix-loop-helix ubiquitous kinase
  • naked mole-rat(101719306) conserved helix-loop-helix ubiquitous kinase

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Phospho-IKKα/β-S176/180 antibody produced in rabbit, ,
Speziesreaktivität
human
Anwendung
western blot
Anti-IKKα Antibody, clone 2M10E3, Rabbit Monoclonal, ,
Speziesreaktivität
mouse
Anwendung
western blot
Anti-CHUK (Ab-23) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-phospho-IKK-α/β (pSer180/181) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot
Anti-p-IKKα/β-Ser176/180 Antibody, clone 2G2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
bovine, canine, feline, human, monkey, mouse, porcine, rat
Anwendung
affinity binding assay
immunohistochemistry

inhibition assay

western blot

Proteins

Produktnummer
Beschreibung
Spezies
IKKα Protein, active, 10 µg, Active, recombinant full-length human IKKα, containing an N-terminal GST-tag, for use in Kinase Assays.,
Spezies
human
IKK α , active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Chuk,
Spezies
mouse
MISSION® esiRNA, targeting human CHUK,
Spezies
human

Small Molecule - Substrate

Produktnummer
Beschreibung
Spezies
IKK Substrate Peptide, ,
Spezies
human