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CHRNA3

cholinergic receptor, nicotinic, alpha 3 (neuronal)

Synonyme:
LNCR2, NACHRA3, PAOD2
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(1136) Summary: This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]
  • Mouse(110834) cholinergic receptor, nicotinic, alpha polypeptide 3
  • Rat(25101) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • Zebrafish(568467) cholinergic receptor, nicotinic, alpha 3
  • dog(482111) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • domestic cat(100037403) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • cow(282702) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • chicken(386578) cholinergic receptor, nicotinic, alpha 3
  • naked mole-rat(101701279) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • domestic guinea pig(100730977) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • sheep(101123239) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • Domestic Rabbit(100342666) cholinergic receptor, nicotinic, alpha 3 (neuronal)

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
(±)-Nikotin, ≥99% (TLC), liquid,
Spezies
human, rat
Carbamoylcholinchlorid, ≥98% (titration), crystalline,
Spezies
human, mouse, rat
Tropisetron -monohydrochlorid, solid, ≥98% (HPLC),
Spezies
rat, human
(−)-Nikotin -Lösung, 1.0 mg/mL, analytical standard, for drug analysis,
Spezies
human, mouse, rat
(−)-Nikotin, ≥99% (GC), liquid,
Spezies
human, mouse, rat

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Cytisin, ≥99%, powder,
Spezies
rat
(±)-Nikotin, ≥99% (TLC), liquid,
Spezies
human, rat
Carbamoylcholinchlorid, ≥98% (titration), crystalline,
Spezies
human, mouse, rat
Mecamylamin -hydrochlorid, ,
Spezies
human
Tropisetron -monohydrochlorid, solid, ≥98% (HPLC),
Spezies
rat, human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CHRNA3 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
dog, human, rabbit
Anwendung
western blot
Monoclonal Anti-Nicotinic Acetylcholine Receptor (α1, α3, α5 Subunits) antibody produced in rat, clone mAb 35, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
chicken, eel, human
Anwendung
immunohistochemistry

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
Tetraethylammoniumchlorid, ≥98% (titration),
Spezies
human
Hexamethoniumbromid, ,
Spezies
human
Hexamethoniumchlorid, solid (hygroscopic),
Spezies
human
Kynurensäure, ≥98%,
Spezies
rat, human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human CHRNA3,
Spezies
human
MISSION® esiRNA, targeting mouse Chrna3,
Spezies
mouse