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Merck

CHRM1

cholinergic receptor, muscarinic 1

Synonyme:
HM1, M1, M1R
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(1128) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008]
  • Mouse(12669) cholinergic receptor, muscarinic 1, CNS
  • Rat(25229) cholinergic receptor, muscarinic 1
  • cow(281684) cholinergic receptor, muscarinic 1
  • Horse(100064117) cholinergic receptor, muscarinic 1
  • domestic cat(101093801) cholinergic receptor, muscarinic 1
  • domestic cat(493664) cholinergic receptor, muscarinic 1
  • dog(483776) cholinergic receptor, muscarinic 1
  • naked mole-rat(101702102) cholinergic receptor, muscarinic 1
  • domestic guinea pig(100728041) cholinergic receptor, muscarinic 1
  • sheep(101117029) cholinergic receptor, muscarinic 1

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Small Molecule - Agonist

Product Number
Beschreibung
Spezies
Pilocarpin -hydrochlorid, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Pilocarpin -hydrochlorid, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Pilocarpinnitrat, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Pilocarpin -hydrochlorid, phyproof® Reference Substance,
Spezies
human
Pilocarpin -hydrochlorid, European Pharmacopoeia (EP) Reference Standard,
Spezies
human

Small Molecule - Antagonist

Product Number
Beschreibung
Spezies
Chinuclidin, 97%,
Spezies
rat
Ethopropazin -hydrochlorid, ≥98% (HPLC), powder,
Spezies
human
Scopolamine Hydrobromide, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Benzatropin -methansulfonat (Salz), ≥98% (HPLC),
Spezies
human
Pirenzepine dihydrochloride, ≥98% (TLC), powder,
Spezies
human

Antibodies

Product Number
Beschreibung
Speziesreaktivität
Anwendung
Anti-Muscarinic Acetylcholine Receptor m1 Antibody, Chemicon®, from rabbit,
Speziesreaktivität
mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-CHRM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-CHRM1 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
western blot
Anti-Muscarinic Acetylcholine Receptor (M1) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Speziesreaktivität
mouse, rat
Anwendung
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
Beschreibung
Spezies
(+)-Pentazocine, solid,
Spezies
rat, human
Amitriptylin -hydrochlorid, ≥98% (TLC), powder,
Spezies
human
Kokain, ,
Spezies
mouse, rat, human
Doxepin -hydrochlorid, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder,
Spezies
human
Haloperidol, powder,
Spezies
human, rat

Small Molecule - Ligand

Product Number
Beschreibung
Spezies
Aminobenztropine, solid,
Spezies
human
Kokain, ,
Spezies
mouse, rat, human

Proteins

Product Number
Beschreibung
Spezies
ChemiScreen Membrane Preparation Human Recombinant M1 Muscarinic Acetylcholine Receptor, Human M1 GPCR membrane prepation for Radioligand binding Assays.,
Spezies
human

esiRNA

Product Number
Beschreibung
Spezies
MISSION® esiRNA, targeting human CHRM1,
Spezies
human