Direkt zum Inhalt
Merck

CCNH

cyclin H

Synonyme:
CAK, p34, p37
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(902) Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Nov 2010]
  • Mouse(66671) cyclin H
  • Rat(84389) cyclin H
  • domestic guinea pig(100726162) cyclin H
  • naked mole-rat(101714118) cyclin H
  • sheep(101104905) cyclin H
  • Zebrafish(541325) cyclin H
  • cow(615512) cyclin H
  • Horse(100065185) cyclin H
  • domestic cat(101095398) cyclin H
  • dog(479156) cyclin H
  • chicken(427328) cyclin H

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CCNH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
Anti-phospho-Cyclin H (pThr315) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
western blot
Anti-Cyclin H Antibody, clone 3N5S3, Rabbit Monoclonal, ,
Speziesreaktivität
mouse
Anwendung
immunofluorescence
immunohistochemistry

western blot
Anti-CCNH antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
western blot

Proteins

Produktnummer
Beschreibung
Spezies
CDK7/Cyclin H1/MNAT1, active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Ccnh,
Spezies
mouse
MISSION® esiRNA, targeting human CCNH,
Spezies
human