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AGTR1

angiotensin II receptor, type 1

Synonyme:
AG2S, AGTR1A, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, AT2R1A, AT2R1B, HAT1R
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(185) Summary: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]
  • naked mole-rat(101714068) angiotensin II receptor, type 1
  • domestic guinea pig(100192325) angiotensin II receptor, type 1
  • sheep(443107) angiotensin II receptor, type 1
  • Domestic Rabbit(100009164) angiotensin II receptor, type 1
  • chicken(396065) angiotensin II receptor, type 1
  • domestic cat(101082936) angiotensin II receptor, type 1
  • dog(403836) angiotensin II receptor, type 1
  • cow(281607) angiotensin II receptor, type 1

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
ProteoMass Angiotensin II MALDI-MS-Standard, vial of 10 nmol,
Spezies
human
[Val5]-Angiotensin II acetate salt hydrate, ≥95% (HPLC), powder,
Spezies
mouse, human, rat
[Asn1, Val5]-Angiotensin II, ≥97% (HPLC),
Spezies
mouse, human, rat

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
Telmisartan, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Valsartan, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Losartan-Kalium, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Valsartan, ≥98% (HPLC),
Spezies
human
Telmisartan, ≥98% (HPLC), solid,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-AT1 Receptor Antibody, Chemicon®, from rabbit,
Speziesreaktivität
human, mouse, rat
Anwendung
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-AGTR1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-AGTR1 Antibody, clone 1I12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
bovine, canine, human, mouse, rat
Anwendung
affinity binding assay
immunocytochemistry

western blot
Anti-AGTR1 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
bovine, dog, guinea pig, human, mouse, rabbit, rat, sheep
Anwendung
western blot
Anti-AT1R/AGTR1 Antibody, clone 8W6G0, Rabbit Monoclonal, ,
Speziesreaktivität
human
Anwendung
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Captopril, ≥98% (HPLC), powder,
Spezies
human, rat
2,2′:5′,2′′:5′′,2′′′-Quaterthiophen, 96%,
Spezies
human, rat, mouse

Proteins

Produktnummer
Beschreibung
Spezies
ChemiSCREEN Human Angiotensin II Receptor, Type I Membrane Preparation, Human AT1 GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human AGTR1,
Spezies
human