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  • Short-term administration of Nicotinamide Mononucleotide preserves cardiac mitochondrial homeostasis and prevents heart failure.

Short-term administration of Nicotinamide Mononucleotide preserves cardiac mitochondrial homeostasis and prevents heart failure.

Journal of molecular and cellular cardiology (2017-09-09)
Rongli Zhang, Yuyan Shen, Lin Zhou, Panjamaporn Sangwung, Hisashi Fujioka, Lilei Zhang, Xudong Liao
ABSTRACT

Heart failure is associated with mitochondrial dysfunction so that restoring or improving mitochondrial health is of therapeutic importance. Recently, reduction in NAD

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
β-Nicotinamide mononucleotide, ≥95% (HPLC)
Sigma-Aldrich
CHAPS hydrate, BioXtra, ≥98% (TLC)
Sigma-Aldrich
Nα-Acetyl-L-lysine
Sigma-Aldrich
ApopTag Peroxidase In Situ Apoptosis Detection Kit, The ApopTag Peroxidase In Situ Apoptosis Detection Kit detects apoptotic cells in situ by labeling & detecting DNA strand breaks by the TUNEL method.