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  • Determination of thiodyglycol in groundwater using solid-phase extraction followed by gas chromatography with mass spectrometric detection in the selected-ion mode.

Determination of thiodyglycol in groundwater using solid-phase extraction followed by gas chromatography with mass spectrometric detection in the selected-ion mode.

Journal of chromatography. A (2001-03-28)
B A Tomkins, G A Sega
ABSTRACT

A highly sensitive analytical procedure is described for determining thiodiglycol in groundwater. Samples are initially fortified with 3,3'-thiodipropanol (surrogate), then both species are extracted using sequential solid-phase extraction with both C18 and Ambersorb 572 columns. The C18 column, which removes extraneous groundwater components, is discarded; the Ambersorb 572 column is dried thoroughly before eluting polar components with a small volume of dichloromethane. The extract is taken to dryness using dry flowing nitrogen, and the resulting residue is derivatized using N-(tert.-butyldimethylsilyl)-N-methyltrifluoroacetamide and pyridine. The derivatized products are diluted to a final volume with toluene, chromatographed using a fused-silica capillary column, and detected with a quadrupole mass spectrometric detector in its selected-ion mode. Two independent, statistically unbiased, procedures were used to evaluate the detection limits for thiodiglycol; the values ranged between 4 and 16 microg(-1) groundwater.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
3,3′-Thiodipropanol, 98%
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