227R-2

BCL6 (EP278) Rabbit Monoclonal Primary Antibody

• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100; 500
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: EP278, monoclonal
• description: (For In Vitro Diagnostic Use in Select Regions (See Chart))
• form: buffered aqueous solution
• species reactivity: human
• packaging: bottle of 1.0 mL predilute (227R-27); bottle of 7.0 mL predilute (227R-28); vial of 0.1 mL concentrate (227R-24); vial of 0.5 mL concentrate (227R-25); vial of 1.0 mL concentrate (227R-26); vial of 0.1 mL concentrate Research Use Only (227R-24-RUO); vial of 1.0 mL concentrate Research Use Only (227R-26-RUO); vial of 1.0 mL pre-dilute Research Use Only (227R-27-RUO); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (227R-28-RUO)
• manufacturer/tradename: Cell Marque^™
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
• isotype: IgG
• control: tonsil
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: nuclear
• Gene Information: human ... BCL6(604)

Description

General description

BCL6 is a transcriptional regulator gene which codes for a 706-amino-acid nuclear zinc finger protein.¹ In normal tissue these antibodies have strong nuclear staining for a subset of B-lymphocytes, mostly located in germinal centers (GC).² BCL6 antibodies stain malignant cells in follicular lymphoma,³ diffuse large B-cell lymphomas,⁴ Burkitt lymphoma,⁴ classical Hodgkin lymphoma,⁵ as well as majority of tumor cells in nodular lymphocyte predominant Hodgkin lymphoma.⁶ BCL6 expression has been also seen in anaplastic large cell lymphomas (ALCL).⁷

Quality

IVD

IVD

IVD

RUO

Linkage

BCL6 Positive Control Slides, Product No. 227S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable