PRPH2
peripherin 2 (retinal degeneration, slow)
Synonyms:
AOFMD, AVMD, CACD2, DS, PRPH, RDS, RP7, TSPAN22, rd2
Species:
Human PRPH2 (5961), Mouse Prph2 (19133), Rat Prph2 (25534), chicken PRPH2 (395899), dog PRPH2 (403972), domestic cat PRPH2 (727697), cow PRPH2 (280907), sheep PRPH2 (101109569), naked mole-rat Prph2 (101702401), domestic guinea pig Prph2 (100713395)
UniProtKB ID:
Gene ID:
- Human(5961) Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic. [provided by RefSeq, Jul 2008]
- Mouse(19133) peripherin 2
- Rat(25534) peripherin 2
- chicken(395899) peripherin 2 (retinal degeneration, slow)
- dog(403972) peripherin 2 (retinal degeneration, slow)
- domestic cat(727697) peripherin 2 (retinal degeneration, slow)
- cow(280907) peripherin 2 (retinal degeneration, slow)
- sheep(101109569) peripherin 2 (retinal degeneration, slow)
- naked mole-rat(101702401) peripherin 2 (retinal degeneration, slow)
- domestic guinea pig(100713395) peripherin 2 (retinal degeneration, slow)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Peripherin-2 Antibody, clone 5H2, clone 5H2, from mouse,
Species Reactivity
bovine, mouse
Application
immunofluorescence
radioimmunoassay
western blot
radioimmunoassay
western blot
Anti-Peripherin Antibody, clone 8G2, culture supernatant, clone 8G2, Chemicon®,
Species Reactivity
bovine, human, mouse, pig, rat
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PRPH2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-Peripherin Antibody, serum, Chemicon®,
Species Reactivity
bovine, human, mouse, pig, rat
Application
immunohistochemistry
western blot
western blot
Anti-Peripherin-2 Antibody, clone 6B10.1, clone 6B10.1, from mouse,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
esiRNA
Product Number
Description
Species