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Merck

PHGDH

phosphoglycerate dehydrogenase

Synonyms:
3-PGDH, 3PGDH, PDG, PGAD, PGD, PGDH, SERA
Species:
UniProtKB ID:
Gene ID:
  • Human(26227) Summary: This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011]
  • Mouse(236539) 3-phosphoglycerate dehydrogenase
  • Rat(58835) phosphoglycerate dehydrogenase
  • Zebrafish(321928) phosphoglycerate dehydrogenase
  • chicken(424381) phosphoglycerate dehydrogenase
  • Horse(100059940) phosphoglycerate dehydrogenase
  • domestic cat(101088505) phosphoglycerate dehydrogenase
  • naked mole-rat(101712402) phosphoglycerate dehydrogenase
  • domestic guinea pig(100726801) phosphoglycerate dehydrogenase
  • cow(505103) phosphoglycerate dehydrogenase
  • sheep(101111328) phosphoglycerate dehydrogenase

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-PHGDH antibody produced in mouse, clone 4A3-1D6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-PHGDH antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-3-PGDH Antibody, clone TK-08 13A8, clone TK-08 13A8, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
Monoclonal Anti-PHGDH antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0555, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-PHGDH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PHGDH,
Species
human