Glycosylation of l,4:3,6-dianhydro-D-glucitol (isosorbide).

Glycosylation of l,4:3,6-dianhydro-D-glucitol (isosorbide).

Carbohydrate research (2004-09-25)

David J Claffey, Mary F Casey, Patrick A Finan

ABSTRACT

Condensation of 2,3,4,6-tetra-O-acetyl-alpha-D-glucopyranosyl-, 2,3,4-tri-O-acetyl-alpha-D-xylopyranosyl- and of 2,3,4,6-tetra-O-acetyl-alpha-D-galactopyranosyl bromides with l,4:3,6-dianhydro-D-glucitol under Koenigs-Knorr conditions, and using the Helferich modification of the reaction showed regioselectivity in glysosylation at C-5 of isosorbide.

MATERIALI

N° Catalogo

Marchio

Descrizione del prodotto

A7562

Sigma-Aldrich

Acetobromo-α-D-galactose, ≥93% (TLC)