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1279804

USP

Fluoxetine hydrochloride

United States Pharmacopeia (USP) Reference Standard

Sinonimo/i:

(±)-N-Methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride, LY-110,140 hydrochloride, Prozac®

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About This Item

Formula empirica (notazione di Hill):
C17H18F3NO · HCl
Numero CAS:
56296-78-7
Peso molecolare:
345.79
Numero MDL:
MFCD00214288
Codice UNSPSC:
41116107
ID PubChem:
329749876
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

fluoxetine

Produttore/marchio commerciale

USP

applicazioni

pharmaceutical (small molecule)

Formato

neat

Stringa SMILE

CNCCC(C1=CC=CC=C1)OC2=CC=C(C(F)(F)F)C=C2.[H]Cl

InChI

1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H
GIYXAJPCNFJEHY-UHFFFAOYSA-N

Informazioni sul gene

human ... SLC6A4(6532)

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Categorie correlate

Applicazioni

Fluoxetine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Azioni biochim/fisiol

Selective serotonin reuptake inhibitor; antidepressant.

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

Note legali

Sold under license from Eli Lilly and Company.
Prozac is a registered trademark of Eli Lilly and Co.

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Fluoxetine Related Compound B, United States Pharmacopeia (USP) Reference Standard

1279837

Fluoxetine Related Compound C, United States Pharmacopeia (USP) Reference Standard

1279815

Fluoxetine Related Compound A, United States Pharmacopeia (USP) Reference Standard

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Fluoxetine hydrochloride, British Pharmacopoeia (BP) Reference Standard

PHR1952

Fluoxetine Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

Y0002201

Fluoxetine impurity A, CRS, European Pharmacopoeia (EP) Reference Standard

Y0002219

Fluoxetine hydrochloride for ID and assay, CRS, European Pharmacopoeia (EP) Reference Standard

Avvertenze

Danger

Indicazioni di pericolo

H302 - H318 - H336 - H373 - H410

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - STOT RE 2 - STOT SE 3

Organi bersaglio

Central nervous system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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R J Gonzalez-Rothi et al.
Chest, 107(6), 1763-1765 (1995-06-01)
We describe a patient who developed progressive dyspnea, lung infiltrates, and restrictive lung disease in association with the antidepressant fluoxetine hydrochloride (Prozac). The pathologic findings were consistent with hypersensitivity pneumonitis. An associated pulmonary phospholipidosis was also noted.
Paulina Jedynak et al.
Journal of psychiatric research, 56, 106-111 (2014-06-17)
The neurogenesis hypothesis of major depression has two main facets. One states that the illness results from decreased neurogenesis while the other claims that the very functioning of antidepressants depends on increased neurogenesis. In order to verify the latter, we
Kristie T Ota et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(3), 711-718 (2014-09-03)
Major depressive disorder (MDD) is a debilitating and widespread illness that exerts significant personal and socioeconomic consequences. Recent genetic and brain-imaging studies suggest that bicaudal C homolog 1 gene (BICC1), which codes for an RNA-binding protein, may be associated with
Sean C Godar et al.
Journal of psychiatric research, 56, 1-9 (2014-06-03)
The termination of serotonin (5-hydroxytryptamine, 5-HT) neurotransmission is regulated by its uptake by the 5-HT transporter (5-HTT), as well as its degradation by monoamine oxidase (MAO)-A. MAO-A deficiency results in a wide set of behavioral alterations, including perseverative behaviors and
Rody Kingston et al.
PLoS genetics, 17(11), e1009885-e1009885 (2021-11-05)
Molecular insights into the selective vulnerability of retinal ganglion cells (RGCs) in optic neuropathies and after ocular trauma can lead to the development of novel therapeutic strategies aimed at preserving RGCs. However, little is known about what molecular contexts determine
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