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H0392

Sigma-Aldrich

Hemoglobin S, Ferrous Stabilized human

lyophilized powder

Sinonimo/i:

Sickle cell hemoglobin

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About This Item

Numero CAS:
9035-22-7
Numero MDL:
MFCD00131288
Codice UNSPSC:
12352202
eCl@ss:
42030116
NACRES:
NA.61

Origine biologica

human

Livello qualitativo

200

Saggio

97-100% (agarose gel electrophoresis)

Forma fisica

lyophilized powder

tecniche

electrophoresis: suitable
immunofluorescence: suitable

Solubilità

H2O: soluble 20 mg/mL

Compatibilità

suitable for electrophoresis and chromatography standard

N° accesso UniProt

P68871

Temperatura di conservazione

−20°C

Informazioni sul gene

human ... HBB(3043)

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Descrizione generale

Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide.
has not been tested for functional equivalence against native preparations (unlyophilized ferrous hemoglobins).

Applicazioni

Hemoglobin S was used in the determination of fetal hemoglobin by time-resolved immunofluorometric assay.

Confezionamento

Package size indicates the amount of hemoglobin as determined by the procedure of Drabkin, D.L., J. Biol. Chem., 164, 703 (1946).

Ricostituzione

When reconstituted with buffer, gives >90% ferrous hemoglobin.

Esclusione di responsabilità

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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U Turpeinen et al.
Clinical chemistry, 38(10), 2013-2018 (1992-10-01)
We have developed a "sandwich"-type time-resolved immunofluorometric assay (IFMA) for fetal hemoglobin (HbF) in hemolysates from adults and newborns, amniotic fluid, and plasma, based on a polyclonal and a monoclonal antibody against human fetal hemoglobin. Microtiter wells are coated with
Brian T Castle et al.
Science advances, 5(3), eaau1086-eaau1086 (2019-03-21)
In sickle cell disease, the aberrant assembly of hemoglobin fibers induces changes in red blood cell morphology and stiffness, which leads to downstream symptoms of the disease. Therefore, understanding of this assembly process will be important for the treatment of
Charles T Quinn et al.
British journal of haematology, 175(4), 724-732 (2016-09-09)
Sickle cell disease (SCD) is a significant healthcare burden worldwide, but most affected individuals reside in low-resource areas where access to diagnostic testing may be limited. We developed and validated a rapid, inexpensive, disposable diagnostic test, the HemoTypeSC

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