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90101

Sigma-Aldrich

Ampliflu Red

for fluorescence, ≥98.0% (HPLC)

Sinonimo/i:

10-Acetyl-3,7-dihydroxyphenoxazine

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About This Item

Formula empirica (notazione di Hill):
C14H11NO4
Numero CAS:
Peso molecolare:
257.24
Numero MDL:
Codice UNSPSC:
12352108
ID PubChem:
NACRES:
NA.32

Grado

for fluorescence

Saggio

≥98.0% (HPLC)

Forma fisica

powder

Fluorescenza

λex 571 nm; λem 585 nm in DMSO

Temperatura di conservazione

2-8°C

Stringa SMILE

CC(=O)N1c2ccc(O)cc2Oc3cc(O)ccc13

InChI

1S/C14H11NO4/c1-8(16)15-11-4-2-9(17)6-13(11)19-14-7-10(18)3-5-12(14)15/h2-7,17-18H,1H3
PKYCWFICOKSIHZ-UHFFFAOYSA-N

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Applicazioni

Ampliflu Red has been used to study mitochondrial abnormalities and oxidative stress related to Parkinson’s Disease. Ampliflu Red assay was suitable as an alternative indicator assay for detecting the inhibition of hTPO (human thyroid peroxidase) activity. Phospholipase D, an essential cellular process ingredient, used Ampliflu Red (10-Acetyl-3,7-dihydroxyphenoxazine) to determine its activity.Ampliflu Red is used for the following applications:
  • Quantification of inflammatory mediators
  • Determination of free and esterified cholesterol contents
  • Evaluation of compounds as substrates for GABA-AT compounds

Note legali

Ampliflu is a trademark of Sigma-Aldrich Co. LLC

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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Macrophages may be a crucial aspect of diabetic complications associated with the inflammatory response. In this study, we examined how hyperglycaemia, a common aspect of diabetes, modulates bone marrow-derived macrophages (BMDMs) under an inflammatory stimulus. To perform this study, BMDMs
Kazuo Sugiyama et al.
PloS one, 9(4), e94460-e94460 (2014-04-11)
Most of experiments for HCV infection have been done using lytic infection systems, in which HCV-infected cells inevitably die. Here, to elucidate metabolic alteration in HCV-infected cells in a more stable condition, we established an HCV-persistently-infected cell line, designated as
Dustin D Hawker et al.
Bioorganic & medicinal chemistry, 20(19), 5763-5773 (2012-09-05)
Two principal neurotransmitters are involved in the regulation of mammalian neuronal activity, namely, γ-aminobutyric acid (GABA), an inhibitory neurotransmitter, and L-glutamic acid, an excitatory neurotransmitter. Low GABA levels in the brain have been implicated in epilepsy and several other neurological
Anne H van der Spek et al.
Endocrine connections, 6(8), 731-740 (2017-11-05)
Innate immune cells have recently been identified as novel thyroid hormone (TH) target cells in which intracellular TH levels appear to play an important functional role. The possible involvement of TH receptor alpha (TRα), which is the predominant TR in
Houjuan Zhu et al.
ACS nano, 11(9), 8998-9009 (2017-08-26)
Development of optical nanotheranostics for the capability of photodynamic therapy (PDT) provides opportunities for advanced cancer therapy. However, most nanotheranostic systems fail to regulate their generation levels of reactive oxygen species (ROS) according to the disease microenvironment, which can potentially

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