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Documenti fondamentali

486R-1

Sigma-Aldrich

Somatostatin Receptor 2A (EP149) Rabbit Monoclonal Primary Antibody

Sinonimo/i:

SSTR2A

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About This Item

Codice UNSPSC:
41116161

Origine biologica

rabbit

Livello qualitativo

Coniugato

unconjugated

Forma dell’anticorpo

IgG fraction of antiserum

Tipo di anticorpo

primary antibodies

Clone

EP149

Descrizione

For In Vitro Diagnostic Use in Select Regions

Stato

buffered aqueous solution

Reattività contro le specie

human

Confezionamento

vial of 0.1 mL (concentrate (486R-14))
vial of 0.1 mL (concentrate (486R-14-RUO) Research Use Only)
vial of 0.5 mL (concentrate (486R-15))
vial of 1.0 mL (concentrate (486R-16))
vial of 1.0 mL (concentrate (486R-16-RUO) Research Use Only)
vial of 1.0 mL (pre-dilute (486R-17-RUO) Research Use Only)
vial of 1.0 mL (pre-dilute ready-to-use (486R-17))
vial of 7.0 mL (pre-dilute ready-to-use (486R-18))
vial of 7.0 mL (pre-dilute ready-to-use (486R-18-RUO) Research Use Only)

Produttore/marchio commerciale

Cell Marque®

tecniche

immunohistochemistry: suitable (formalin-fixed, paraffin-embedded sections 1:25-1:100 (concentrated))

Isotipo

IgG

Controllo

lymph node, pancreas, (meningioma)

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Visualizzazione

cytoplasmic (
), membranous

Descrizione generale

Somatostatin Receptor 2A (SSTR2A) is a protein highly expressed in pancreas binding somatostatin and inhibiting pancreatic enzyme secretion. SSTR2A is used as a marker for identifying meningioma from other spindle-cell tumors such as solitary fibrous tumor. SSTR2A is more frequently expressed in higher grade meningiomas and associated to its microvessel proliferation. SSTR2A has demonstrated utility as a diagnostic marker for follicular dendritic cell sarcomas and some other related tumors.

Qualità

United States - IVD
Canada - RUO
European Union - IVD
Japan - RUO

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota sulla preparazione

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Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2


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Camille Boulagnon-Rombi et al.
Journal of neuropathology and experimental neurology, 76(4), 289-298 (2017-03-25)
The differential diagnosis between meningioma and others tumors can be challenging. This study aimed to evaluate different immunohistochemical markers for the differential diagnosis between meningioma and their morphological mimics. Immunohistochemistry was performed on tissue microarray with antiepithelial membrane antigen (EMA)
Balrik Kailey et al.
American journal of physiology. Endocrinology and metabolism, 303(9), E1107-E1116 (2012-08-31)
Somatostatin-14 (SST) inhibits insulin and glucagon secretion by activating G protein-coupled somatostatin receptors (SSTRs), of which five isoforms exist (SSTR1-5). In mice, the effects on pancreatic β-cells are mediated by SSTR5, whereas α-cells express SSTR2. In both cell types, SSTR

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