00541

Ruthenium Red

for microscopy, 85.0-115.0% (calc. on dry basis, AT)

• Sinonimo/i: Ammoniated ruthenium oxychloride
• Formula condensata: [(NH₃)₅RuORu(NH₃)₄ORu(NH₃)₅]Cl₆
• Numero CAS: 11103-72-3
• Peso molecolare: 786.35
• Colour Index: 77800
• Numero MDL: MFCD00011479
• Codice UNSPSC: 12171500
• ID PubChem: 329747091
• NACRES: NA.47

Proprietà

• Grado: for microscopy
• Livello qualitativo: 100
• Saggio: 85.0-115.0% (calc. on dry basis, AT)
• Forma fisica: powder
• Impurezze: ~5% water
• Solubilità: water: 10 mg/mL, clear to turbid
• εmax: ≥150 at 529-539 nm
• applicazioni: diagnostic assay manufacturing; hematology; histology
• Temperatura di conservazione: room temp
• Stringa SMILE: N.N.N.N.N.N.N.N.N.N.N.N.N.N.[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Ru++]O[Ru++]O[Ru++]
• InChI: 1S/6ClH.14H3N.2O.3Ru/h6*1H;14*1H3;;;;;/q;;;;;;;;;;;;;;;;;;;;;;3*+2/p-6; ZXYSDUPLHOJIOR-UHFFFAOYSA-H

Descrizione

Descrizione generale

Ruthenium red is an inorganic cationic dye. It is also known as ammoniated ruthenium oxychloride. It is a large coordination complex consisting of three metal atoms connected by bridging oxygens, in addition to multiple amine ligands.

Applicazioni

Ruthenium red is suitable for use in light microscopy to stain pectins. It is also used to stain glycosaminoglycans by employing a two-color staining method with alcian blue. It serves as a typical basic dye at a higher pH that stains nuclei, Nissl substance, cartilage matrix, and mast cell granules. Other applications involving light microscopy include staining resin-embedded material. Ruthenium red is an important component of fixatives of the bacterial glycocalyx.

Inhibits mitochondrial Ca²⁺ uniporter; capsaicin antagonist; blocks VR1 vanilloid receptor-coupled ion channels.

Azioni biochim/fisiol

Ruthenium red inhibits mitochondrial Ca2+ uniporter. It is a known capsaicin antagonist. Additionally, it is known to block VR1 vanilloid receptor-coupled ion channels.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H302
• Consigli di prudenza: P264 - P270 - P301 + P312 - P501
• Classi di pericolo: Acute Tox. 4 Oral
• Codice della classe di stoccaggio: 13 - Non Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable